Anti Fungal and Coatings
Project B3.1 Development of Antimicrobial Coatings for Steel Surfaces
Fouling of Bluescope’s COLORBOND roofing materials by fungal colonies is a key commercial innovation for the company. Fungal growth is primarily an aesthetic problem but also degrades the thermal efficiency of some buildings. The goal of this activity is surface coatings that interfere with the fundamental mechanisms that allow fungal materials to adhere to roofing materials while maintaining the aesthetic and durability properties of the product.
Project B3.2 Molecular Modelling of Fundamental Molecular Mechanisms of Initial Microbial Adhesion to Functional Surfaces
Based on the latest advancements in molecular dynamics modelling, this project aims to identify an appropriate approach to multiscale modelling of functional surfaces and their interaction with microbial proteins. Following this, a comprehensive methodology will be developed which will enable the modelling of various combinations of surfaces/functional ligands/proteins and environmental conditions such as temperature, hydration and pH levels. Ultimately, this should assist in better understanding how proteins behave at various solid/liquid interfaces, so as to rationally design and produce surfaces which control their adsorption.
Project B3.3 Design and characterization of mechano-fungicidal surfaces
Based on the underlying physical principal associated with biocidal effect of insect wings, other topologies that may possess surface architectures that exhibit structurally induced antimicrobial characteristics might be investigated. The investigation will extend to other types of the nano-patterned surfaces, both natural and artificial. Given the biocidal action of the autogenous surfaces is mechanical in nature, this project is focusing on the relationship between the surface structures and their biocidal behavior against fungal cells.
Project B3.4: Coarse-grained Molecular Dynamics Simulations of the Effects of Surface Topography on Disruption of Fungal Membranes
Following other related Project B3 activities, this project will use coarse-grain molecular dynamics calculations to simulate the interaction of fungal membranes with surfaces of different topography, and to use these results to guide development of materials with identified topographies that exert destructive forces that compromise membrane structure.
B4.1- SECM for Development of Antifungal Coatings for Painted Steel Surfaces
This short-term research activity will use the Scanning Electrochemical Microscope (SECM) technique for more rapid assessment of antifungal coating systems developed in-house, so as to optimise prototypes and provide confidence in accelerated testing of the longevity of such systems.